1st GPCR Zoominar

Tobias Benkel
(ISAR Bioscience GmbH, Germany)
"Towards a rational design of β-adrenoceptor ligands - G protein- versus arrestin-mediated signaling of Carvedilol"

Dylan S. Eiger 
(Duke University Health System, USA)
"Phosphorylation barcodes direct biased chemokine signaling at CXCR3"

Recorded on January 26, 2023

2nd GPCR Zoominar

Berna Doğan
(Bahcesehir University, Turkey)
"Exploring the conformational heterogeneity of HIV-1 coreceptor CCR5 by Molecular Dynamics"

Alejandro Peralta Garcia and Marta López Balastegu 
(Universitat Pompeu Fabra, Spain)
"New tools on GPCRmd: cryptic pockets and variant mapping"

Recorded on February 9, 2023

3rd GPCR Zoominar

Laura Humphrys
(University of Regensburg, Germany)
"Bioluminescence biosensors for G protein selectivity of the dopamine receptor and their ligands"

Mithu Baidya 
(Indian Institute of Technology Jammu, India)
"Receptor phosphorylation pattern drives β-arrestin conformation"

Recorded on March 9, 2023

3rd GPCR Zoominar

Laura Humphrys
(University of Regensburg, Germany)
"Bioluminescence biosensors for G protein selectivity of the dopamine receptor and their ligands"

Mithu Baidya 
(Indian Institute of Technology Jammu, India)
"Receptor phosphorylation pattern drives β-arrestin conformation"

Recorded on March 9, 2023

4th GPCR Zoominar

Fengjie Wu
(University of Basel, Switzerland)
"Nanobody GPS by PCS: An Efficient New NMR Analysis Method for GPCRs and Other Large Proteins"

Julia Gardner 
(Duke University, USA)
"Subcellular localization of GPCR kinases differentially modulate biased CXCR3 signaling"

Recorded on March 23, 2023

6th GPCR Zoominar

Annabelle Milner
(Imperial College London, UK)
"The differential effects of L- and D-lactate on HCAR1 signalling"

Benjamin Myers 
(University of Utah, USA)
"Unconventional GPCR-PKA Communication in the Hedgehog Pathway"

Recorded on April 6, 2023

9th GPCR Zoominar

Shannon O'Brien
(University of Brimingham, UK)
"Spatio-temporal control of G protein-coupled receptor activity: Investigating FFAR4 signalling in adipocytes"

Berkay Selcuk 
(Sabanci University, Turkey)
"Evolutionary association of receptor-wide amino acids with G protein-coupling selectivity in aminergic GPCRs"

Recorded on May 11, 2023

10th GPCR Zoominar

Alessandro Nicoli
(Leibniz Institute for Food Systems Biology at the Technical University of Munich, Germany)
"Molecular Recognition of the neuropeptide Y by the Y1 receptor"

Katie Sharrocks 
(Imperial College London, UK)
"A mutagenesis-based approach to stabilise D2 dopamine receptor homomers"

Recorded on May 25, 2023

11th GPCR Zoominar

Luca Chiesa
(University of Strasbourg, France)
"Detection of β2-adrenergic receptor agonists using single-ligand dynamic interaction data"

Lukas Grätz 
(Karolinska Institute, Sweden)
"Pathway Selectivity in Frizzleds is Achieved by Conserved Microswitches Defining Pathway-Determining, Active Conformations"

Recorded on June 22, 2023

12th GPCR Zoominar

Daniel Hilger
(Philipps-University Marburg, Germany)
"Insights into the molecular mechanism of glucagon receptor signaling and its modulation by RAMP2"

Maria Florencia Sánchez
(Goethe University Frankfurt, Germany)
"Ligand-free in situ confinement for receptor activation and signal transduction"

Recorded on July 6, 2023

13th GPCR Zoominar

Xiangyu Liu
(School of Pharmaceutical Sciences, Tsinghua University, China)
"Structural biology and drug innovation for the beta adrenergic receptors"

Jie Heng
(Shuimu BioSciences Ltd., China)
"Dynamic modulation of GPCR signaling complexes"

Recorded on July 27, 2023

14th GPCR Zoominar

Silvia Sposini
(Imperial College London, UK, and the Interdisciplinary Institute for Neurosciences in Bordeaux, France)
"Characterization of neuromodulator receptors trafficking using the ppH assay"

Amod Godbole
(University Hospital Jena, Germany)
"Differences in GRK/arrestin-mediated regulation of adenosine receptors"

Recorded on September 21, 2023

15th GPCR Zoominar

Anemari Horvat
(University of Ljubljana, Slovenia)
"Octopamine/tyramine GPCR expression and neurodegenerative changes in aging Drosophila brain"

Tomasz Stępniewski  
(Hospital del Mar, Spain/ InterAx Biotech, Switzerland)
"Novel roles of the membrane in GPCR modulation - insights from molecular dynamic simulations"

Recorded on October 5, 2023

16th GPCR Zoominar

Lauri Urvas
(University of Strasbourg, France)
"Benchmarking AlphaFold-generated structures of chemokine - chemokine receptor complexes"

Claire A. de March
(Paris Saclay University, France)
"Structural elucidations of mammalian odorant receptors"

Recorded on October 19, 2023

17th GPCR Zoominar

Romy Thomas
(Max-Delbrück-Centre Berlin, Germany)
"Novel fluorescence biosensor technology to map extracellular GPCR conformations"

Janik Hedderich
(Philipps-University Marburg, Germany)
"The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites"

Recorded on November 2, 2023

18th GPCR Zoominar - Café session 

Katarzyna Marcinkiewicz
(Senior editor Nature Communications, New York office)

Recorded on November 22, 2023

19th GPCR Zoominar

Shanu Jain
(Indian Institute of Technology Kanpur, India)
"GPCRs in Metabolic Disorders: Obesity, Type 2 Diabetes, and MAFLD"

Sanduo Zheng
(NIBS, China)
"KCTD family, emerging regulators of GPCR signaling"

Recorded on November 30, 2023

20th GPCR Zoominar

Marie-Lise Jobin
(Institut National Polytechnique de Bordeaux, France)
"Filamin A key role on GPCR dynamics and signaling by fluorescence microscopy"

Recorded on December 14, 2023